As a result of an oil platform in the Gulf of Mexico exploding, a mutant seemingly composed of living fire emerges. As this creature goes on a rampage in the area looking for more combustible substances upon which to feed, H.E.A.T and Godzilla intervene. However, the creature grows larger and more powerful as a result of absorbing and feeding off of Godzilla's powerful incendiary breath.

During its latest creature investigations, H.E.A.T. splits up into two teams, one of which investigates a group of mutant parasitic organisms in Florida, whereas the second group handles a case of a giant, mutated, and rapidly growing multi-tentacled fungi-like creature in Michigan.

Another new and dangerous mutant species appears on the scene, this time in the form of gigantic hummingbirds that attack planes flying over San Francisco. Worst of all, this mutant avian species is able to render themselves invisible via the hummingbird trait of flapping their wings faster than any other bird species in the world. As a result of their ability to cloak themselves so as to be invisible to the unaided eye, Godzilla is unable to see the creatures in order to attack them.

Cameron Winter returns to take yet another shot at H.E.A.T. and Godzilla, this time enlisting the aid of the three redneck, would-be-killers of the Big G from the previous episode ""Cat and Mouse,"" and equipping them with powerful machines of destruction (sometimes referred to as 'Battle Mechs'--another thank you to Doc Psy from Centropoholics:). Godzilla, H.E.A.T., and a military unit commanded by Major Hicks battle the machines and destroy them, and the three violent hicks are arrested.

Both H.E.A.T. and Major Hicks learn that an old comrade of the Major named Colonel Charles Thompson has been overseeing black ops military funded scientific experiments designed to create enormous, genetically altered scorpions for use as bio-weapons, in a multi-level program referred to as the First Wave. The largest scorpion produced by this experiment, however, breaks loose from the military's control, forcing H.E.A.T. to send Godzilla after the arachnoid beast. However, Godzilla is given supreme opposition, not only from the beast's lethal stinger, but also from its ability to spray poison at a distance from that aforementioned stinger. Finally, H.E.A.T. works together to discover a way to cause the more easily-controlled smaller scorpions to attack the larger one, after which Godzilla annhiliates the entirety of the First Wave with his incendiary breath. Despite the chewing out that Col. Thompson receives from Major Hicks, the former nevertheless orders the Second Wave of th

While conducting another creature investigation in the valley of Blind Rock, Wyoming, H.E.A.T. meets up with a girl whose brother went missing after he entered an abandoned mine in the area where the sightings took place. Upon entering the mine themselves, the group discovers one of the strangest mutations they have yet encountered, a huge two-headed kaiju known as the Silver Hydra, on account of the fact that it has the ability to spurt a silvery fluid that hardens once it surrounds a living being, thus transforming them into the equivalent of a silver statue, a fate that obviously befell the girl's brother.

H.E.A.T. tackles a gigantic mutant shrew-like creature, which has somehow merged itself with an artificially generated, experimental tornado, enabling it to transform itself into a living vortex at will (Elsie wittily dubs the whirling beast 'The Shrewster'). In order to maintain its ultra-fast, whirlwind powers, the Shrewster is forced to rapidly consume three times its body weight per day, thus causing it to greedily devour every organic food source in its path, effectively making it an extremely dangerous menace. Because of its ability to transform itself into an organic tornado, Godzilla is unable to get at the beast, and Tatopoulos ends up trapped in the Shrewster's vortex. However, soon after becoming trapped, he activates a device that Craven crafted, which was designed to dissipate the vortex's cyclonic forces, and this succeeds.

H.E.A.T. investigates the legendary “Area 51” in Nevada and discovers its true secret is not alien landings, but giant mutated desert creatures created by decades of underground nuclear testing.